Louisville, Kentucky Mayor Craig Greenberg said:

“Rachel and I are praying for the victims of the UPS plane crash that occurred during takeoff at 5:15 p.m. Every emergency agency is responding to the scene. There are multiple injuries, and the fire is still burning.

Numerous roads in the area are closed—please stay clear of the scene. The plane was carrying 280,000 gallons of fuel. We will be holding a briefing soon with Governor Beshear and will share more details as they become available.”